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Previous Ace Report Evicel fibrin sealant does not appear to reduce total blood loss/transfusion rates for TKA Next Ace Report Evicel fibrin sealant does not appear to reduce total blood loss/transfusion rates for TKA
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Arthroplasty
Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients
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Arthroplasty
Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients
J Arthroplasty. 2014 Aug;29(8):1528-31
Contributing Authors

JN Patel JM Spanyer LS Smith J Huang MR Yakkanti AL Malkani

89 patients undergoing unilateral total knee arthroplasty were randomly assigned to receive either topical Tranexamic Acid or Intravenous Tranexamic Acid. This study aimed to compare the efficacies of each route of administration on the reduction of blood loss following primary total knee arthroplasty. Results suggested no statistical difference in the perioperative change in hemoglobin levels between the two groups, and no differences in the number of transfusions required.

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OrthoEvidence. Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients. ACE Report. 2014;4(10):37. Available from: https://myorthoevidence.com/AceReport/Report/

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