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GENERAL ORTHOPAEDICS
Methadone PCA may be used as a first-line drug for acute pain management following THA
This report has been verified
by one or more authors of the
original publication.
J Anesth. 2014 Aug;28(4):505-10. doi: 10.1007/s00540-013-1785-3. Epub 2014 Jan 21.
Thirty four patients undergoing elective total hip arthroplasty were randomized to a methadone or morphine patient-controlled analgesia (PCA) system for the first 24 hours post-surgery with the purpose of comparing the analgesia effect between the two groups. Methadone PCA resulted in less opioid consumption and lower pain scores in the first 24 hours postoperative, while the proportion of patients who reported adverse effects was similar between groups.
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