
Arthroplasty
THR: Celecoxib more effective than ibuprofen in prevention of heterotopic bone formation
J Bone Joint Surg Br. 2007 Feb;89(2):155-9.250 patients with severe hip osteoarthritis were randomized to either receive ibuprofen or celecoxib to determine the relative benefits of these drugs in preventing heterotopic ossification following total hip replacement (THR). The results at 3 months post-op indicated that a ten day trial of celecoxib during the post-op period reduced the risk of heterotopic ossification.
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