ARTHROPLASTY
TKA: Topical Fibrin Spray and Tranexamic acid reduce blood loss
J Bone Joint Surg Br. 2007 Mar;89(3):306-9150 patients undergoing total knee replacement surgery were randomized to either receive topical fibrin spray, tranexamic acid, or to a control group which received no pharmacological treatment. This study aimed to compare the efficacy of these blood management treatments. The results indicated that both the topical fibrin spray and tranexamic acid were effective in reducing blood loss following this operation, in comparison to those receiving no pharmacological treatment. However, there was no significant difference between these two interventions.
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