28 patients with a grade II hamstring injury were allocated to undergo daily home-based rehabilitation exercises, and randomized to either receive or not receive an injection of platelet-rich plasma upon presentation to the sports medicine clinic. Participants were followed-up for time to return to play, as well as improvement of pain. Mean time to return to play was 27 days in the PRP group and 42.5 days in the control group, and log-rank test for return to play revealed significantly quicker return to play among the group who received PRP injection compared to those who did not.