11 randomized controlled trials (N=1092) comparing therapeutic aquatic exercise (TAE) with no intervention in patients with lower limb osteoarthritis (OA) were included in this systematic review/meta-analysis. The purpose of this study was to evaluate the effects of TAE on symptoms and function associated with lower limb OA. The outcomes of interest were pain, stiffness, patient-reported function, physical functioning (activities, muscle strength, and joint range of motion), and quality of life. Pooled data indicated superior results in patients who underwent TAE therapy for all outcome measurements except muscle strength.