GENERAL ORTHOPAEDICS
Oral administration of salmon calcitonin for postmenopausal women with low bone mass
Osteoporos Int. 2014 Nov;25(11):2649-56129 postmenopausal women with low bone mass were randomly assigned to receive either salmon calcitonin orally or placebo once daily for 1 year. The outcomes of interest were the change in bone mineral density (at the lumbar spine, femoral neck, trochanter, and total hip) and collagen type 1 C-telopeptide (CTx-1). The findings demonstrated a significant increase in lumbar spine bone mineral density in the calcitonin group compared with the placebo group, and a significantly smaller reduction in proximal femur bone mineral density in the calcitonin group compared to the palcebo group over 54 weeks.
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