116 patients who underwent primary total knee arthroplasty were quasi-randomized to either receive advanced cryotherapy or the use of cold packs (control) to compare VAS pain, narcotic consumption, range of motion, swelling, and blood loss postoperatively between groups. The purpose of this study was to determine whether or not computer-assisted cryotherapy is superior compared to cold pack application after knee replacement. Results revealed no significant difference in VAS pain, narcotic consumption, functional outcomes, swelling, and blood loss between groups.