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OSTEOARTHRITIS
Brands and risk of bias lead to inconsistency in trials on glucosamine use for arthritis
This report has been verified
by one or more authors of the
original publication.
Arthritis Care Res (Hoboken). 2014 Dec;66(12):1844-55.
This meta-analysis evaluated 25 randomized control trials which assessed the efficacy of glucosamine for pain due to osteoarthritis (OA), when compared to a placebo group. The study included a total of 3,458 patients who were assessed over short- (at least 4 weeks) or long-term (up to 3 years) periods. The purpose of the study was to determine factors which may account for inconsistencies between trials regarding the efficacy of glucosamine as a treatment for OA. Results indicated that the brand of glucosamine used, and the risk of bias of each study greatly affected variance in outcome results between studies.
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