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Zoledronic acid reduces rates of new clinical fractures after hip fracture repair
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Zoledronic acid reduces rates of new clinical fractures after hip fracture repair

N Engl J Med. 2007 Nov 1;357(18):1799-809. Epub 2007 Sep 17

Contributing Authors

KW Lyles CS Colón-Emeric JS Magaziner JD Adachi CF Pieper C Mautalen L Hyldstrup C Recknor L Nordsletten KA Moore C Lavecchia J Zhang P Mesenbrink PK Hodgson K Abrams JJ Orloff Z Horowitz EF Eriksen S Boonen HORIZON Recurrent Fracture

2127 patients were randomized to one of two groups to examine the rates of new clinical fractures after hip fracture repair. The first group received an annual infusion of zoledronic acid (a potent bisphosphonate), while the second group received a placebo. Results indicated that an annual infusion of zoledronic acid is associated with reduced rates of new clinical fractures and subsequently, morbidity.

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OrthoEvidence. Zoledronic acid reduces rates of new clinical fractures after hip fracture repair. ACE Report. 2013;3(8):166. Available from: https://myorthoevidence.com/AceReport/Report/

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