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METABOLIC DISORDERS
Early bisphosphonate use after surgery does not appear to delay fracture healing
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Osteoporos Int. 2015 Feb;26(2):431-41.
Contributing Authors

YT Li HF Cai ZL Zhang

10 studies with a total of 2888 patients in total were included in this meta-analysis and systemic review examining the use of bisphosphonates (BPs) in patients following a surgical procedure to treat a fracture. The purpose of the study was to determine whether early use of bisphosphonates (within 3 months of surgery) would have a negative impact on fracture healing time or not. The results indicated that patients receiving bisphosphonate therapy had similar radiological fracture healing times when compared to patients in the control group. Furthermore, rates of delay or nonunion of fracture healing were similar between early and delayed BP therapy groups.

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OrthoEvidence. Early bisphosphonate use after surgery does not appear to delay fracture healing. ACE Report. 2015;5(5):37. Available from: https://myorthoevidence.com/AceReport/Report/

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