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Arthroplasty
Aprotinin reduces blood transfusion in patients undergoing total hip arthroplasty
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Arthroplasty
Aprotinin reduces blood transfusion in patients undergoing total hip arthroplasty
Clin Orthop Relat Res. 2007 Dec;465:189-95
Contributing Authors

Colwell CW JE Chelly JM Murkin D Stevens TJ O'Keefe R Hall J Parvizi

393 patients undergoing elective primary total hip arthroplasty (THA) were randomized to receive aprotinin (a blood-conserving drug) or a placebo. The primary outcomes were the requirement for transfusions and blood loss. Results from this study indicated the use of aprotinin significantly reduces the requirement for blood transfusions when compared to a placebo treatment. No significant differences in adverse events were observed between the aprotinin and placebo treatments.

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OrthoEvidence. Aprotinin reduces blood transfusion in patients undergoing total hip arthroplasty. ACE Report. 2013;3(8):173. Available from: https://myorthoevidence.com/AceReport/Report/

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