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Previous Ace Report Effects of vitamin D and whole body vibration training for institutionalized elderly women Next Ace Report Immediate effects of ankle pushoff instructions during walking exercise on hip kinetics
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Osteoarthritis
Topical NSAIDs equally effective as oral NSAIDs for knee pain, with fewer adverse effects
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Osteoarthritis
Topical NSAIDs equally effective as oral NSAIDs for knee pain, with fewer adverse effects
BMJ. 2008 Jan 19;336(7636):138-42. Epub 2007 Dec 4.
Contributing Authors

Martin Underwood Deborah Ashby Pamela Cross Enid Hennessy Louise Letley Jeannett Martin Shahrul Mt-Isa Suzanne Parsons Madge Vickers Ken Whyte

282 people, aged 50 years or older, with knee pain on most days for at least a month were randomized to the use of a topical or an oral NSAID for a 24 month period. It was observed that both modes of administration were equally efficacious in pain control according to WOMAC (Western Ontario and McMaster Universities) osteoarthritis index. Furthermore, the topical route reported fewer respiratory side effects and lesser impact on the renal function compared to NSAIDs administered orally.

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OrthoEvidence. Topical NSAIDs equally effective as oral NSAIDs for knee pain, with fewer adverse effects. ACE Report. 2013;3(3):136. Available from: https://myorthoevidence.com/AceReport/Report/

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