14 studies, including 8 randomized controlled trials, were included in this meta-analysis which had the purpose of evaluating the prophylactic effects of preventative neuromuscular training in female athletes afflicted with anterior cruciate ligament injuries. The four types of exercise in the training program – balance, proximal control, strength, and plyometrics – were evaluated in subgroup analyses to determine efficacy in terms of number of anterior cruciate ligament injuries incurred during the intervention. The results of this study indicated that strength and proximal control training offered the greatest benefits in terms of preventing injury. However, no significant reduction was seen in the incidence of injuries in patients who engaged in balance or plyometric activities in comparison to those who did not. Additionally, subgroup analysis indicated that a combination of multiple exercise types significantly enhances prophylactic effectiveness compared to neuromuscular training programs that incorporated only one type of exercise.