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Previous Ace Report Epidural steroid injection versus gabapentin for relief from lumbosacral radicular pain Next Ace Report Epidural steroid injection versus gabapentin for relief from lumbosacral radicular pain
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Arthroplasty
TXA is effective and safe for reducing blood loss and transfusion in TKA patients
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Arthroplasty
TXA is effective and safe for reducing blood loss and transfusion in TKA patients
Eur J Orthop Surg Traumatol. 2015 Apr;25(3):525-41
Contributing Authors

Q Wu HA Zhang SL Liu T Meng X Zhou P Wang

34 randomized controlled trials (2,594 patients) were used in this meta-analysis analyzing the safety and efficacy of tranexamic acid (TXA) in patients undergoing primary total knee arthroplasty (TKA). Pooled results demonstrated intravenous (IV) and intraarticular (IA) use of TXA significantly reduced total blood loss, postoperative blood loss, hemoglobin (Hb) loss, and blood transfusion without increasing the risk of deep vein thrombosis (DVT) or other adverse effects.

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OrthoEvidence. TXA is effective and safe for reducing blood loss and transfusion in TKA patients. ACE Report. 2015;5(6):14. Available from: https://myorthoevidence.com/AceReport/Report/

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