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ISAKOS 2015: PRP & HMWHA injections effective in degenerative knee cartilage lesions

48 male soccer players, with evidence of degenerative cartilage lesions were randomized to receive either injections of platelet-rich plasma (PRP) or high molecular weight hyaluronic acid (HMWHA). The purpose of the study was to determine the efficacy of both treatments in patients over a 12 month period. Results indicated that patients responded well to both treatments, with significantly better improvements in knee scores seen in the PRP group at 3 and 6 months follow-up. However, both treatments were similarly effective after 12 months.

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. ISAKOS 2015: PRP & HMWHA injections effective in degenerative knee cartilage lesions. ACE Report. 2015;5(6):29. Available from: https://myorthoevidence.com/AceReport/Report/

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