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ISAKOS 2015: PRP has better pain and function at 6 months than HA in knee OA

111 patients were randomized to receive either platelet-rich plasma (PRP) or hyaluronic acid (HA) in the treatment of knee osteoarthritis. The purpose of this study was to compare pain, function and biologic factors measured up to 6 months after treatment. Results found that PRP provided significantly greater improvements in pain and function over the 6 month period. Further assessments are needed to confirm these findings and evaluate the effectiveness of PRP in the treatment of knee osteoarthritis over a longer follow-up period.

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. ISAKOS 2015: PRP has better pain and function at 6 months than HA in knee OA. ACE Report. 2015;5(6):30. Available from: https://myorthoevidence.com/AceReport/Report/

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