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Osteoarthritis
ISAKOS 2015: Platelet-Rich Plasma favourable compared to acetaminophen for primary knee OA
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Osteoarthritis
ISAKOS 2015: Platelet-Rich Plasma favourable compared to acetaminophen for primary knee OA

Contributing Authors

F Vilchez M Simental C Acosta Mendoza S Said H Martinez

49 patients with primary knee osteoarthritis were randomized to receive treatment of either acetaminophen or platelet-rich plasma (PRP), to assess and compare the clinical outcomes resulting from the two treatments. The concentration of IL-1ra in the platelet-rich-plasma group was also evaluated. The study found that patients in the platelet-rich plasma group displayed significantly less pain, and better function. In addition, patients in this group had levels of IL-1ra sufficient to inhibit IL-1B activity.

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OrthoEvidence. ISAKOS 2015: Platelet-Rich Plasma favourable compared to acetaminophen for primary knee OA. ACE Report. 2015;5(6):34. Available from: https://myorthoevidence.com/AceReport/Report/

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