57 adult patients that were candidates for total knee arthroplasty (TKA) were randomized into 2 groups either receiving computer-assisted surgery or conventional TKA. The purpose of the study was to determine the difference in embolic burden between these techniques. The results indicated that mean embolic scores were significantly lower in the computer-assisted surgery group, yet this outcome may not be clinically significant as there were no significant differences in fat emboli. A larger sample size is needed to determine if there are significant differences in fat emboli between these procedures.