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Effect of antibiotic prophylaxis duration on infection after spinal surgery with drains
J Bone Joint Surg Am. 2015 Jun 17;97(12):979-86

314 patients who underwent multilevel thoracolumbar spinal surgery followed by the use of a postoperative drain were randomized to either receive antibiotic prophylaxis for 24 hours, or for the entire duration the drain was in place. The purpose of the study was to compare infection rates between these groups within 1 year of surgery. Results indicated that infection rates were similar between groups. No increased risk of infection was detected when comparing revision cases with primary cases.

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  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. Effect of antibiotic prophylaxis duration on infection after spinal surgery with drains. ACE Report. 2015;5(9):14. Available from: https://myorthoevidence.com/AceReport/Report/

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