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Tanezumab: A future option for pain control in knee osteoarthritis?
N Engl J Med. 2010 Oct 14;363(16):1521-31.

450 patients (age range 40 to 75) with knee osteoarthritis were randomized to receive either different dosages of the Tanezumab (an inhibitor of nerve growth factor) or a placebo, in order to determine the safety and efficacy of the Tanezumab treatment. The Tanezumab treatment group was observed to have reduced pain and improved function of the arthritic knee joint.

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  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. Tanezumab: A future option for pain control in knee osteoarthritis?. ACE Report. 2013;3(3):169. Available from: https://myorthoevidence.com/AceReport/Report/

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