ARTHROPLASTY
Addition of diluted epinephrine to topical TXA for reducing blood loss in THA
J Arthroplasty. 2015 Dec;30(12):2196-200107 patients scheduled for total hip arthroplasty without the use of postoperative drains were randomized to be administered topical tranexamic acid (TXA) with or without the addition of diluted epinephrine (DEP). The purpose of this study was to evaluate if the addition of DEP to topical TXA significantly reduced haemtological parameters associated with blood loss and allogeneic blood transfusion. The incidence of deep vein thrombosis and pulmonary embolism were also monitored. Calculated total blood loss and hidden blood loss were significantly lower in the TXA+DEP group compared to the TXA group. No difference was observed between groups for intraoperative blood loss. The difference between groups in the incidence of transfusion was not statistically significant.
Unlock the full ACE Report
You have access to {0} free articles per month.Click below to unlock and view this {1}
Unlock NowCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidence content for just $1.99 per week.
Already have an account? Log in
Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.
{0} of {1} free articles
Become an OrthoEvidence Premium Member. Expand your perspective with high-quality evidence.
Upgrade Now
