
Shoulder & Elbow
PRP does not affect clinical outcome of acromioplasty in rotator cuff tendinopathy
This report has been verified
by one or more authors of the
original publication.
Am J Sports Med. 2015 Dec;43(12):2891-7
60 patients with rotator cuff tendinopathy (subacromial impingement or partial thickness tear) were randomized to receive arthroscopic acromioplasty with or without an additional injection of platelet-rich plasma (PRP). The purpose of this randomized controlled trial was to assess whether PRP injection affected clinical outcomes and histological tissue characteristics. The results displayed no significant differences between the two groups in terms of Oxford Shoulder Scores, VAS pain, satisfaction, or quality of life at 2 years postoperatively. The patients treated with PRP displayed decreased numbers of blood vessels and tendon cellularity, with increased expression of p53 (apoptosis marker), in the tendon biopsy. Bonar scoring displayed no significant changes in tissue structure between groups.
Unlock the full article
Get unlimited access to OrthoEvidence with a free trial
Start TrialCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or continue reading this full article
Register Now

Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.