SPINE
Use of platelet-rich plasma for treatment of symptomatic degenerative lumbar disease
PM R. 2016 Jan;8(1):1-1058 patients with low back pain due to degenerative lumbar disease were randomized to intradiscal injection of 1-2mL of either platelet-rich plasma (PRP) or contrast agent (Omnipaque 180). The purpose of this study was to evaluate the efficacy of PRP for improvement of measures of pain and function relative to a nonactive injection. Follow-up was performed over 8 weeks post-injection. Results after 8 weeks were mixed; significant differences in favor of PRP injection versus control were observed for the Functional Rating Index (FRI) and Numeric Rating Scale (NRS) of best pain, although no significant between-group differences were observed for NRS current pain and worst pain, or Physical Function and Pain dimensions of the SF-36.
Unlock the full ACE Report
You have access to {0} free articles per month.Click below to unlock and view this {1}
Unlock NowCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidence content for just $1.99 per week.
Already have an account? Log in
Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.
{0} of {1} free articles
Become an OrthoEvidence Premium Member. Expand your perspective with high-quality evidence.
Upgrade Now
