6 randomized controlled trials (n= 408 patients, 447 knees) were included in this meta-analysis and systematic review for the purpose of comparing femoral nerve block (FNB) and adductor canal block (ACB) for postoperative pain and quadriceps muscle strength following total knee arthoplasty. Pooled results demonstrated that postoperative pain between study groups was comparable at 4, 24, and 48 hours. Qualitative analysis additionally demonstrated a possible benefit of ACB on quadriceps recovery, particularly within 8 hours, though inconsistent results among studies warrant additional research into this outcome of patient recovery.