OSTEOARTHRITIS
No beneficial effects of oral vitamin D3 on cartilage volume or knee pain in knee OA
This report has been verified
by one or more authors of the
original publication.
JAMA. 2016 Mar 8;315(10):1005-13
413 patients with knee osteoarthritis and low vitamin D levels were randomized to a monthly treatment of either oral vitamin D3 or an identical placebo for 24 months. The purpose of this study was to determine whether or not vitamin D supplements are beneficial in mitigating knee pain and improving knee cartilage volume, when compared with placebo up to 2 years. Findings indicated no significant difference in changes in tibial cartilage volume, WOMAC knee pain, tibiofemoral cartilage defects, or tibiofemoral bone marrow lesions between treatment groups.
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