
Metabolic Disorders
WCO-IOF 2016: Greater BMD increase after 1 year of romosozumab vesus teripratide
436 postmenopausal women with osteoporosis who had been administered oral bisphosphonate therapy for 3 years prior were randomized in a phase 3 clinical trial to subcutaneous romosozumab or subcutaneous teriparatide. The purpose of this study was to compare the change in bone mineral density after 1 year of treatment between the two groups. Reported results demonstrated a significantly greater increase in total hip and lumbar spine BMD in the romosozumab group compared to the teriparatide group.
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