Home
ACE Reports
All Specialties All Specialties All Specialties Arthroplasty Arthroplasty Arthroplasty Evidence Based Medicine Evidence Based Medicine Evidence Based Medicine Foot & Ankle Foot & Ankle Foot & Ankle General Orthopaedics General Orthopaedics General Orthopaedics Hand & Wrist Hand & Wrist Hand & Wrist Metabolic Disorders Metabolic Disorders Metabolic Disorders Osteoarthritis Osteoarthritis Osteoarthritis Pediatric Orthopaedics Pediatric Orthopaedics Pediatric Orthopaedics Peri-Operative Peri-Operative Peri-Operative Physical Therapy & Rehab Physical Therapy & Rehab Physio & Rehab Shoulder & Elbow Shoulder & Elbow Shoulder & Elbow Spine Spine Spine Sports Medicine Sports Medicine Sports Medicine Trauma Trauma Trauma Tumour Tumour Tumour Author Interviews Author Interviews Author Interview Conference Report Conference Report Conference Reports
Original Content
News
All News All News All News Biologics Biologics Biologics Industry Industry Industry Innovation Innovation Innovation Research Research Research Studies Studies Studies Technology Technology Technology Other Other Other
Multimedia
All Themes All Themes All Themes Education Education Education Innovation Innovation Innovation Leadership Leadership Leadership Personal Growth Personal Growth Personal Growth Practice Practice Practice Research Research Research Other Other Other OrthoJoe OrthoJoe OrthoJoe Webinar Webinar Webinar OE Headline OE Headline OE Headline OrthoPod OrthoPod OrthoPod
About
Search
Home
ACE Reports
Arthroplasty Evidence Based Medicine Foot & Ankle General Orthopaedics Hand & Wrist Metabolic Disorders Osteoarthritis Pediatric Orthopaedics Peri-Operative Physical Therapy & Rehab Shoulder & Elbow Spine Sports Medicine Trauma Tumour Author Interviews Conference Report
Original Content
News
Biologics Industry Innovation Research Studies Technology Other
Multimedia
Education Innovation Leadership Personal Growth Practice Research Other OrthoJoe Webinar OE Headline OrthoPod
About
Search
AceReport Image
OSTEOARTHRITIS
Autologous PRP vs. HA injections for pain, function, activity improvement in knee OA
Verified
This report has been verified by one or more authors of the original publication.
Int J Mol Sci. 2016 Jul 2;17(7).
Contributing Authors

E Montañez-Heredia S Irízar PJ Huertas E Otero M Del Valle I Prat MS Díaz-Gallardo M Perán JA Marchal C Hernandez-Lamas Mdel

55 patients with Kellgren-Lawrence grade I-III knee osteoarthritis were randomized to receive either intraarticular injections of autologous platelet-rich plasma (PRP) or hyaluronic acid (HA). The purpose of this study was to compare these two injection therapies in terms of improvement in pain, function, and daily/sports activity, assessed at 3 or 6 months post-treatment. The results of this trial demonstrated comparable improvement between interventions at both time-points. In a subgroup of patients with KL grade II knee OA only, treatment with PRP injections resulted in significantly greater improvement in KOOS activities of daily life scores after 3 and 6 months, pain after 6 months, and sports & recreation activity after 6 months when compared to HA injections.

Unlock the full ACE Report

You have access to {0} free articles per month.
Click below to unlock and view this {1}
Unlock Now

Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics

Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics

Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions

Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics

Or upgrade today and gain access to all OrthoEvidence content for just $1.99 per week.
{0} of {1} free articles

Become an OrthoEvidence Premium Member. Expand your perspective with high-quality evidence.

Upgrade Now
You've reached your limit of 4 free articles views this month

Access to OrthoEvidence for as little as $1.99 per week.

Stay connected with latest evidence. Cancel at any time
  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Upgrade Account
Upgrade
Search
Popular searches: Knee OA, PRP, What is the efficacy for prolotherapy for rotator cuff tendinopathy?
Are suture buttons or screw fixations more effective for syndesmosis injuries?
Close Search Window
Welcome Back!
Forgot Password?
Start your FREE trial today!

Account will be affiliated with

OR
Forgot Password?
OR
Please check your email

If an account exists with the provided email address, a password reset email will be sent to you. If you don't see an email, please check your spam or junk folder.

For further assistance, contact our support team.

Cite this Ace Report

OrthoEvidence. Autologous PRP vs. HA injections for pain, function, activity improvement in knee OA . ACE Report. 2016;6(9):32. Available from: https://myorthoevidence.com/AceReport/Report/

Copy Citation
Share this Ace Report