70 patients with knee osteoarthritis (Kellgren-Lawrence grades 2-4) were randomized to treatment with either a transcutaneous electrical nerve stimulation (TENS) knee brace for 3 months or standard of care. Patients were followed up for a minimum of 1-year, evaluating pain, function, and health-related quality of life. Results demonstrated no significant differences between groups for these outcomes at 1-year. Within-group assessments indicated that the TENS group experienced significant improvement in function compared to baseline, and a trend towards significantly improved pain.