Arthroplasty
OTA 2016: Assessing the efficacy & safety of TXA in arthroplasty for femoral neck fracture
138 patients with a femoral neck fracture scheduled for total hip arthroplasty were randomized to be managed with either tranexamic acid or placebo. Calculated total blood loss, transfusion requirement, and adverse events/complications were assessed. The tranexamic acid group demonstrated a statistically significant 305mL reduction in total blood loss compared to the placebo group, though no significant difference was noted in the incidence of transfusion between groups.
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