OSTEOARTHRITIS
Corticosteroids improve pain and symptoms over the short-term in knee OA
BMJ. 2004 Apr 10;328(7444):869. Epub 2004 Mar 23.
Ten randomized controlled trials were included in this meta-analysis to evaluate the efficacy of intra-articular corticosteroid injections compared to placebo for the management of knee osteoarthritis. A dichotomous outcome of symptom improvement, defined as the most important patient-oriented outcome, and pain outcome were evaluated. Corticosteroid injections resulted in a favourable outcome for symptom improvement and a significant reduction in pain over the short term (2 weeks). Symptom improvement at 16-24 weeks favoured corticosteroid injection, but was based on data from only 2 studies. Additional trials using homogenous outcome measures are needed to add to the body of evidence.
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