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Previous Ace Report Topical TXA and IV TXA similarly effective in reducing blood loss in tourniquetless TKA Next Ace Report Prolonged use of corticosteroid injections for knee osteoarthritis reduces cartilage volume
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Arthroplasty
Intracapsular and intravenous administration for TXA similar in efficacy and safety in TKA
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Arthroplasty
Intracapsular and intravenous administration for TXA similar in efficacy and safety in TKA
J Arthroplasty. 2016 Nov;31(11):2452-2457
Contributing Authors

JH May GR Rieser RJ Markert RD Bauman CG Williams MW Lawless

131 patients scheduled for total knee arthroplasty were randomized to tranexamic acid administration via intracapsular injection at the end of the procedure or intravenous injections before and after the procedure. The purpose of this study was to compare blood loss, hemoglobin levels, transfusion rate, and thromboembolic complication rate between groups over the first 3 days postoperatively. Results demonstrated no significant differences between groups in any outcome measure.

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OrthoEvidence. Intracapsular and intravenous administration for TXA similar in efficacy and safety in TKA. ACE Report. 2017;7(6):1. Available from: https://myorthoevidence.com/AceReport/Report/

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