
Arthroplasty
Efficacy of fibrin sealant in total hip and total knee arthroplasty
Int J Surg. 2016 Dec;36(Pt A):127-13718 randomized controlled trials were included in this meta-analysis investigating the efficacy and safety of fibrin sealant on reducing blood loss in total knee arthroplasty and total hip arthroplasty. Control groups consisted of either no fibrin sealant administration or placebo administration. Analyses demonstrated significantly lower incidence of transfusion and significantly lower total blood loss among fibrin sealant groups in both total knee arthroplasty and total hip arthroplasty.
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