TRAUMA
IV TXA 15mg/kg reduces blood loss and transfusion in fixation of trochanteric fracture
J Orthop Surg (Hong Kong). 2016 Dec;24(3):379-38260 patients with a stable trochanteric fracture scheduled for internal fixation with a dynamic hip screw were randomized to pre-incision intravenous administration of a 15mg/kg dose of tranexamic acid or 0.9% normal saline. The purpose of this study was to compare intraoperative blood loss, postoperative blood loss, transfusion requirement and the incidence of complications between groups. Results demonstrated significantly lower intraoperative blood loss, postoperative blood loss up to 48 hours after surgery, and requirement of transfusion in the group administered tranexamic acid compared to saline. No cases of thromboembolic complications were recorded in either group.
Unlock the full ACE Report
You have access to {0} free articles per month.Click below to unlock and view this {1}
Unlock NowCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidence content for just $1.99 per week.
Already have an account? Log in
Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.
{0} of {1} free articles
Become an OrthoEvidence Premium Member. Expand your perspective with high-quality evidence.
Upgrade Now
