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AAOS2017: Addition of epimorph associated with higher pain after TKA vs spinal anaesthesia

82 patients scheduled for total knee arthroplasty were randomized to spinal anesthesia with or without the addition of epimorph 150ug. Patients were assessed for pain scores, narcotic consumption, and the incidence of opioid-related adverse events, such as nausea, vomiting, and pruritus, over the first 48 hours postoperatively. Results demonstrated significantly higher pain scores in the spinal epimorph group compared to the control group at 18, 24, and 48 hours postoperatively, along with higher rates of nausea and pruritus.

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. AAOS2017: Addition of epimorph associated with higher pain after TKA vs spinal anaesthesia. ACE Report. 2017;7(3):48. Available from: https://myorthoevidence.com/AceReport/Report/

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