99 patients scheduled for total shoulder arthroplasty were randomized to postoperative analgesia with either local infiltration analgesia or a continuous interscalene block for 48 hours postoperatively. Patients were assessed for perioperative pain and opioid consumption, as well as functional outcome at 1-month follow-up. Within the recovery room, LIA demonstrated significantly lower pain scores and opioid consumption compared to the ISB group; differences between groups were non-significant after 48 hours.
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