50 patients scheduled for total knee arthroplasty were randomized to either perioperative gabapentin or placebo administration. Patients were assessed on postoperative days 0, 1, and 2 for pain scores on a visual analog scale, narcotic consumption, and knee range of motion. Results demonstrated no significant difference in VAS pain scores between groups on POD0-2, or in narcotic consumption on POD0. Narcotic consumption on POD1 and 2 was significantly lower in the gabapentin group compared to the placebo group.
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