61 patients undergoing arthroscopic ACL reconstruction using a hamstring tendon autograft were randomized to undergo intraoperative local anesthetic infiltration at the graft harvest site or traditional local anesthetic. Postoperative pain and analgesic consumption were evaluated over the first 48 postoperative hours. There were no significant differences in postoperative pain, however, analgesic consumption was significantly lower in the group of patients that underwent anesthetic infiltration at the donor site. A significant reduction was also observed when evaluating opiate consumption only.