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Previous Ace Report Mini-invasive intramedullary pin vs. locking compression plate for midshaft clavicle fractures Next Ace Report Assessing the efficacy of topical ketoprofen versus active- and placebo-comparators for knee OA
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Osteoarthritis
Either etodolac 400mg bid or naproxen 500mg bid effective versus placebo in knee OA treatment
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Osteoarthritis
Either etodolac 400mg bid or naproxen 500mg bid effective versus placebo in knee OA treatment
Clin Ther. 1995 Jul-Aug;17(4):656-66
Contributing Authors

R Dore I Ballard G Constantine P McDonald

254 patients with symptomatic knee osteoarthritis were randomized to receive either etodolac 400mg, naproxen 500mg, or placebo for 4 weeks. Patients were assessed for clinical efficacy using Patients' and Physicians' Global Assessments, and safety was assessed using the incidence of adverse events. Both etodolac and naproxen demonstrated significantly better results for clinical efficacy compared to placebo, with no significant differences between etodolac and naproxen.

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OrthoEvidence. Either etodolac 400mg bid or naproxen 500mg bid effective versus placebo in knee OA treatment. ACE Report. 2017;7(9):32. Available from: https://myorthoevidence.com/AceReport/Report/

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