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Previous Ace Report ACL remnant preservation versus resection in arthroscopic anterior cruciate ligament reconstruction Next Ace Report Comprehensive Geriatric Assessment vs. Conventional Post-Op Rehab in Elderly Patients with Hip Frx
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Arthroplasty
Assessment of IV, IA, and oral tranaexamic acid safety in total joint arthroplasty
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Arthroplasty
Assessment of IV, IA, and oral tranaexamic acid safety in total joint arthroplasty
J Arthroplasty. 2018 Oct;33(10):3083-3089.e4. doi: 10.1016/j.arth.2018.06.023
Contributing Authors

CJ Della Valle EH Schemitch SG Memtsoudis HD Clarke AP Sah D Jevsevar SA Sayeed RL Johnson YA Fillingham DB Ramkumar AJ Yates P Shores K Mullen SA Bini

78 randomized controlled trials were included in this meta-analysis, which sought to evaluate the incidence of venous and arterial thromboembolic (VTE and ATE) events associated either intravenous, intraarticular, and oral tranexamic acid, and compare rates to placebo or control intervention groups. No analysis demonstrated a significant increase in the risk of VTE or ATE complications with either intravenous TXA, intraarticular TXA, or oral TXA.

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OrthoEvidence. Assessment of IV, IA, and oral tranaexamic acid safety in total joint arthroplasty. ACE Report. 2018;8(11):11. Available from: https://myorthoevidence.com/AceReport/Report/assessment-of-iv-ia-and-oral-tranaexamic-acid-safety-in-total-joint-arthroplasty

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