41 postmenopausal women who suffered a unilateral distal radius fracture (DRF) were included in the study in order to assess the effect of nasal salmon calcitonin on post-fracture pain. Patients were randomized to receive either 200 IU of intranasal salmon calcitonin or a placebo. The study found a greater decrease in pain during the first post-fracture period (10 days) compared to baseline in the calcitonin group; however, there were no difference in absolute VAS pain scores at any time point. It should be noted that this study was limited by its small sample size.