37 individuals with mild-to-moderate knee osteoarthritis were randomized to determine the effect of group-based cycling. Participants were allocated to either 12 weeks of stationary cycling, or to a control group where they were encouraged to continue physical activity as normal. Outcomes of interest were improvement in pain, lower-body muscle strength, and self-reported pain, stiffness, function, and knee-related QoL. The results after 12 weeks indicated that cycling increased preferred walking speed, pain after walking, and subscales of pain, stiffness, and activities of daily living throughout three self-reported instruments. Improvement in muscle strength did not differ significantly between groups after 12 weeks.