74 patients, scheduled to undergo primary total knee arthroplasty, were randomly assigned into 1 of 4 prosthetic groups: high-flexion mobile bearing, high-flexion fixed bearing, conventional fixed bearing, and conventional mobile bearing. The purpose was to compare the migration and clinical outcomes of high-flexion total knee arthroplasty with fixed or mobile bearings versus the conventional counterparts. Results of the study demonstrated that high-flexion knee prostheses with a mobile or fixed bearing led to comparable tibial and femoral component migration (2 to 5 years postoperatively) when compared to their conventional counterparts.