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Previous Ace Report Intermittent versus continuous ropivacaine infusion and the impact on interscalene block efficacy Next Ace Report Comparison of neuromuscular exercise therapy and pharmacological intervention for knee OA
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Arthroplasty
IA-TXA effective compared to placebo for blood loss and transfusion reduction in TKA
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Arthroplasty
IA-TXA effective compared to placebo for blood loss and transfusion reduction in TKA
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This report has been verified by one or more authors of the original publication.
J Knee Surg. 2018 Jan;31(1):56-67
Contributing Authors

JT Moskal SG Capps

Sixteen studies were included in this meta-analysis, which compared the effect of intra-articular tranexamic acid to placebo for outcomes related to blood loss, transfusion rate, and adverse events. Pooled analyses demonstrated significant differences in favour of IA-TXA for all efficacy outcomes, including total blood loss, postoperative blood loss, transfusion rate, and hemoglobin drop. Rates of complications, including wound complications and thromboembolic complications, did not significantly differ between groups in pooled analyses.

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OrthoEvidence. IA-TXA effective compared to placebo for blood loss and transfusion reduction in TKA. ACE Report. 2019;9(2):24. Available from: https://myorthoevidence.com/AceReport/Report/ia-txa-effective-compared-to-placebo-for-blood-loss-and-transfusion-reduction-in-tka

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