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Previous Ace Report ISAKOS2017: Additional lidocaine patch further reduces pain alongside standard analgesic plan in TKA Next Ace Report ISAKOS2017: Quadruple-stranded hamstring tendon vs patellar tendon autografts in ACL reconstruction
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Arthroplasty
ISAKOS2017: Comparison of safety and efficacy between topical and IV tranexamic acid in TKA
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Arthroplasty
ISAKOS2017: Comparison of safety and efficacy between topical and IV tranexamic acid in TKA
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J Dong B Chen HT Xu

Eight randomized controlled trials were included in this meta-analysis comparing the efficacy and safety of topical and intravenous tranexamic acid for use in total knee arthroplasty. Total blood loss, postoperative blood loss, hemoglobin (Hb) drop, transfusion rate, and the incidence of complications were pooled. No significant differences between groups were noted, with the exception of Hb drop at 24 hours. Despite the difference observed at 24 hours, Hb drop did not significantly differ at 48 hours between topical and IV groups.

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OrthoEvidence. ISAKOS2017: Comparison of safety and efficacy between topical and IV tranexamic acid in TKA. ACE Report. 2017;7(7):43. Available from: https://myorthoevidence.com/AceReport/Report/isakos2017-comparison-of-safety-and-efficacy-between-topical-and-iv-tranexamic-acid-in-tka

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