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Previous Ace Report Use of mobile device for radiographic assessment of ankle injuries is reliable Next Ace Report Use of mobile device for radiographic assessment of ankle injuries is reliable
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Arthroplasty
Metal-on-metal THA increases HLA DR+CD8+ T-cells & correlates with immunological reactions
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Arthroplasty
Metal-on-metal THA increases HLA DR+CD8+ T-cells & correlates with immunological reactions
Acta Orthop. 2011 Feb;82(1):6-12. Epub 2010 Dec 29
Contributing Authors

NP Hailer RA Blaheta H Dahlstrand A Stark

85 patients undergoing total hip arthroplasty (THA) were randomized to receive either a metal-on-metal bearing or a metal-on-polyethylene prosthesis. The primary outcome was elevation of circulating HLA DR+ CD8+ T-cells and correlation with chromium and cobalt concentrations. Results indicated that metal-on-metal THA increased chromium and cobalt concentrations which resulted in a correlation in immunological reactions. This was associated with the increase in HLA DR+CD8+ T-cells and a decrease in B-cells.

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OrthoEvidence. Metal-on-metal THA increases HLA DR+CD8+ T-cells & correlates with immunological reactions. ACE Report. 2013;3(4):126. Available from: https://myorthoevidence.com/AceReport/Report/metal-on-metal-tha-increases-hla-dr-cd8-t-cells-correlates-with-immunological-reactions

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