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Previous Ace Report Preoperative IV methylprednisolone does not mitigate loss of flexion-extension strength after TKA Next Ace Report E. coli-derived rhBMP-2 offers similar fusion success to AIBG in posterolateral lumbar fusion
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Arthroplasty
Neither additional IV nor oral acetaminophen enhances multimodal analgesia efficacy in TKA
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Arthroplasty
Neither additional IV nor oral acetaminophen enhances multimodal analgesia efficacy in TKA
J Arthroplasty. 2017 Oct;32(10):3029-3033
Contributing Authors

C Zhang J Wang Y Gu Y Jiang JB O'Neal AA Freiberg MD Yelle X Kong W Jian WT O'Neal

174 patients scheduled for primary unilateral total knee arthroplasty were randomized to postoperative intravenous acetaminophen, postoperative oral acetaminophen, or postoperative placebo, all of these treatments were given in addition to a multimodal analgesia regimen. Patients were assessed for analgesia outcomes, including pain scores and opioid consumption, within the postanaesthesia care unit and over the first 24 hours postoperatively. Results demonstrated no significant differences between the three groups for any outcome measured.

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OrthoEvidence. Neither additional IV nor oral acetaminophen enhances multimodal analgesia efficacy in TKA. ACE Report. 2018;8(1):19. Available from: https://myorthoevidence.com/AceReport/Report/neither-additional-iv-nor-oral-acetaminophen-enhances-multimodal-analgesia-efficacy-in-tka

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