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Previous Ace Report The effect of platelet-rich plasma on outcomes following ACL reconstruction Next Ace Report The effect of platelet-rich plasma on outcomes following ACL reconstruction
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Osteoarthritis
No benefit to hyaluronic acid over placebo for knee OA pain and function
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Osteoarthritis
No benefit to hyaluronic acid over placebo for knee OA pain and function
J Arthroplasty. 2015 May;30(5):754-7.
Contributing Authors

W van der Weegen JA Wullems E Bos H Noten RA van Drumpt

196 patients were randomized to receive either hyaluronic acid (HA) or a placebo in knee osteoarthritis (OA) treatment. HA was compared to placebo to test the efficacy in reduction of pain and function. Results of this study found no significant benefit of HA treatment over placebo for visual analogue score, Western Ontario and McMaster Universities Arthritis Index (WOMAC), or knee flexion. However, both groups demonstrated significant improvement from baseline values to 6 month follow-up.

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OrthoEvidence. No benefit to hyaluronic acid over placebo for knee OA pain and function. ACE Report. 2015;5(8):1. Available from: https://myorthoevidence.com/AceReport/Report/no-benefit-to-hyaluronic-acid-over-placebo-for-knee-oa-pain-and-function

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