80 patients with elbow tendinopathy and scheduled for needle tenotomy were randomized to adjuvant intratendinous injection or either platelet-rich plasma or lidocaine. Intratendinous injections were performed within areas of hypoechogenicity observed during ultrasound-guided tenotomy. Primary outcomes were the proportion of patients who demonstrated minimum reductions of 25% from baseline in the Disabilities of the Arm, Shoulder, and Hand (DASH) and pain on a visual analog scale (VAS). Results demonstrated no significant differences between groups in responders for both measures from 6 weeks to 1 year following treatment.