81 patients scheduled for primary total knee arthroplasty for the treatment of knee osteoarthritis were randomized to receive wound closure with the knee either in flexion (90deg) or extension. Outcomes of interest included the knee and function sub-scores of the American Knee Society Score (AKSS), knee range of motion in flexion, and isokinetic muscle strength (peak torque, total work, peak torque difference, total work difference). Follow up was performed up to 6 months post-operation. Results revealed no significant differences in all outcomes between the closure in flexion and closure in extension groups.